SCHEMBL7769401

SCHEMBL7769401

CC(=O)[N]NC(=O)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771624 0.75 CA2 (0.42) L3MBTL1ALDH1A1
SCHEMBL7770033 0.75 L3MBTL1 (0.32) L3MBTL1
SCHEMBL7771366 0.72 TSHR (0.34) L3MBTL1TSHR
SCHEMBL7765719 0.69 ALDH1A1 (0.39) ALDH1A1TP53TSHR
SCHEMBL13436162 0.65 CRBN (0.41) L3MBTL1ALDH1A1TP53TSHR
SCHEMBL7770990 0.65
SCHEMBL7765741 0.65 ALDH1A2 (0.34) ALDH1A1
SCHEMBL245714 0.64
SCHEMBL4395089 0.63 L3MBTL1 (0.30) L3MBTL1
SCHEMBL712181 0.62 ALDH1A1 (0.44) L3MBTL1ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed