Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7768572 | 0.82 | GLA (0.41) | LMNAMEN1KMT2AGLANPC1 | |
| SCHEMBL7772529 | 0.82 | SMN1; SMN2 (0.47) | LMNAMEN1KMT2ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL7769436 | 0.79 | RAB9A (0.51) | LMNAKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL7769549 | 0.72 | ADRB2 (0.52) | PGRADRB2ADRB1ADRB3LMNA | |
| SCHEMBL6321975 | 0.71 | LMNA (0.51) | PGRADRB2ADRB1ADRB3LMNA | |
| SCHEMBL6322046 | 0.70 | ADRB3 (0.63) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL6322039 | 0.70 | ADRB3 (0.63) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7769501 | 0.68 | KMT2A (0.39) | KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7701751 | 0.68 | ADRB3 (0.66) | PGRADRB2ADRB1ADRB3LMNA | |
| SCHEMBL9654060 | 0.68 | LMNA (0.38) | PGRADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107944-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-20 | — | — | EP | disclosed |
| WO-2000012462-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA 3 ADRENERGIC AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-09 | — | — | WO | disclosed |