Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330581 | 0.83 | SMN1; SMN2 (0.74) | MAPTKDM4ENPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL31302688 | 0.83 | SMN1; SMN2 (0.74) | MAPTKDM4ENPSR1HSD17B10SMN1; SMN2 | |
| SCHEMBL4580492 | 0.82 | KDM4E (0.82) | MAPTKDM4ENPSR1HTTUSP2 | |
| SCHEMBL8892044 | 0.79 | CASP1 (0.50) | MAPT | |
| SCHEMBL8891364 | 0.78 | CASP1 (0.49) | MAPTKDM4ENPSR1HTTUSP2 | |
| SCHEMBL16371128 | 0.77 | KDM4E (0.77) | MAPTKDM4ENPSR1HTTUSP2 | |
| SCHEMBL24355418 | 0.76 | KDM4E (0.97) | MAPTKDM4ENPSR1HTTUSP2 | |
| SCHEMBL7776116 | 0.75 | NPC1 (0.70) | MAPTKDM4EUSP2HSD17B10POLB | |
| SCHEMBL4753148 | 0.74 | KDM4E (0.70) | MAPTKDM4ENPSR1HTTHSD17B10 | |
| SCHEMBL16392457 | 0.74 | SMN1; SMN2 (0.97) | MAPTKDM4EUSP2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574906-B1 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO (JP) | 2001-08-22 | — | — | EP | claimed |
| US-5380724-A | Inhibitors of lipid peroxidation | GYOGYSZERKUTATO INTEZET KFT (HU) | 1995-01-10 | — | — | US | claimed |