Sugi Predict

Sugi Predict / Compounds / SCHEMBL7769888

SCHEMBL7769888

SCHEMBL7769888

Cc1ccc(N(c2ccccc2C)c2ccc(-c3ccc(N(c4ccc(C)cc4)c4ccccc4C)c(C)c3)cc2C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B1 P14061 4/20 0.38
▸ HSD17B2 P37059 4/20 0.38
▸ TSHR P16473 3/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ HPGD P15428 2/20 0.32
▸ HTT P42858 1/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ C5AR1 P21730 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2A6 P11509 1/20 0.32
▸ TDP1 Q9NUW8 2/20 0.31
▸ CYP3A4 P08684 2/20 0.31
▸ ESR1 P03372 1/20 0.31
▸ MAPT P10636 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17734489 0.90 HSD17B1 (0.35) HSD17B1HSD17B2ALDH1A1HPGDMAPT
SCHEMBL17734510 0.90 HSD17B1 (0.35) HSD17B1HSD17B2ALDH1A1HPGDMAPT
SCHEMBL7772390 0.89 CYP3A4 (0.33) HSD17B1HSD17B2TSHRALDH1A1CYP2C19
SCHEMBL14732535 0.88 CYP2C19 (0.38) TSHRALDH1A1CYP2C19HPGDMEN1
SCHEMBL7764386 0.88 CYP2C19 (0.38) TSHRALDH1A1CYP2C19HPGDMEN1
SCHEMBL2533406 0.87 CYP1A2 (0.38) HSD17B1HSD17B2TSHRALDH1A1CYP2C19
SCHEMBL30441321 0.87 ALDH1A1 (0.39) HSD17B1HSD17B2TSHRALDH1A1CYP2C19
SCHEMBL142025 0.87 ALDH1A1 (0.39) HSD17B1HSD17B2TSHRALDH1A1CYP2C19
SCHEMBL13480247 0.87 TSHR (0.42) HSD17B1HSD17B2TSHRALDH1A1CYP2C19
SCHEMBL17734525 0.87 HSD17B1 (0.37) HSD17B1HSD17B2ALDH1A1HPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160133847-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-05-12 — — US disclosed
US-20160133847-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2016-05-12 — — US disclosed
EP-0863441-B1 Electrophotographic imaging member XEROX CORP (US) 2001-06-20 — — EP disclosed
US-6127077-A Photoreceptors with delayed discharge XEROX CORPORATION (US) 2000-10-03 — — US disclosed
US-6071662-A SUPPORTING SUBSTRATE HAVING ELECTROCONDUCTIVE SURFACE AND BACKED WITH ANTI-CURL LAYER COMPRISING A POLYCARBONATE BINDER FILM CONTAINING 3,3,5-TRIMETHYLCYCLOHEXANE GROUPS IN THE POLYCARBONATE MOIETY XEROX CORPORATION (US) 2000-06-06 — — US disclosed
US-6068960-A Methods to prepare photoreceptors with delayed discharge XEROX CORPORATION (US) 2000-05-30 — — US disclosed
US-6020096-A MIXTURE OF ACID, CHARGE TRANSPORTATION COMPOUND, FILM FORMING POLYMER AND POLYETHER BLOCK POLYMER XEROX CORPORATION (US) 2000-02-01 — — US disclosed
US-5882831-A N-ALKYLPIPERIDINE OR TRIETHYLAMINE OR COMPLEX WITH PROTONIC OR LEWIS ACID XEROX CORPORATION (US) 1999-03-16 — — US disclosed
EP-0863441-A1 Electrophotographic imaging member XEROX CORPORATION (US) 1998-09-09 — — EP disclosed
US-5709974-A IMAGING MEMBER WITH SUPPORT CARRYING A CHARGE GENERATING LAYER, CHARGE TRANSPORT LAYER AND OVERCOATING LAYER XEROX CORPORATION (US) 1998-01-20 — — US disclosed
EP-0529878-B1 Photoreceptor containing similar charge transporting small molecule and charge transporting polymer XEROX CORP (US) 1997-02-26 — — EP disclosed
EP-0529877-B1 Photoreceptor containing dissimilar charge transporting small molecule and charge transporting polymer XEROX CORP (US) 1996-11-13 — — EP disclosed
EP-0434368-B1 Electrophotographic imaging members XEROX CORP (US) 1996-04-03 — — EP disclosed
US-5316880-A Multilayer electrography imaging member with charge generating and charge transport layers on films XEROX CORPORATION (US) 1994-05-31 — — US disclosed
EP-0529877-A1 Photoreceptor containing dissimilar charge transporting small molecule and charge transporting polymer XEROX CORPORATION (US) 1993-03-03 — — EP disclosed
EP-0529878-A1 Photoreceptor containing similar charge transporting small molecule and charge transporting polymer XEROX CORPORATION (US) 1993-03-03 — — EP disclosed
US-5028502-A Charge Transport Layer Containing Polystyrene Film Forming Binder And An Aromatic Diamine Or Hydrazone Compound XEROX CORPORATION (US) 1991-07-02 — — US disclosed
EP-0434368-A2 Electrophotographic imaging members XEROX CORPORATION (US) 1991-06-26 — — EP disclosed
US-4988595-A MULTILAYER ELECTROPHOTOGRAPHIC IMAGING MEMBER, CHARGE TRANSPORT LAYER AND CHARGE GENERATING COMPOUND XEROX CORPORATION (US) 1991-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160133847-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT ARL1, CCNL2, APOL1 HSD17B1 2383/4885HSD17B2 2310/4885TSHR 3851/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.