Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308455 | 0.90 | INSR (0.40) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15768617 | 0.88 | MEN1 (0.38) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL29573024 | 0.88 | MEN1 (0.38) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL14047730 | 0.88 | SMN1; SMN2 (0.35) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL20149501 | 0.88 | ALDH1A1 (0.42) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL13480247 | 0.88 | TSHR (0.42) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL7769888 | 0.87 | HSD17B1 (0.38) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL19270230 | 0.86 | TDP1 (0.39) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL19958560 | 0.86 | ALDH1A1 (0.41) | CYP1A2CYP2A6MAPTTP53SMN1; SMN2 | |
| SCHEMBL8943789 | 0.85 | ACHE (0.45) | CYP1A2CYP2A6MAPTTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694744-B1 | OLIGOMERS AND POLYMERS | MERCK PATENT GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| EP-1694744-B1 | OLIGOMERS AND POLYMERS | MERCK PATENT GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1694744-A1 | OLIGOMERS AND POLYMERS | MERCK PATENT GmbH (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056638-A1 | OLIGOMERS AND POLYMERS | MERCK PATENT GMBH (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080217605-A1 | Oligomers and Polymers | AR, ARPC3, NMRAL1 | CYP1A2 2375/4885CYP2A6 3695/4885MAPT 344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.