SCHEMBL7776157

SCHEMBL7776157

COc1ccc(S(=O)(=O)NC(=O)c2ccc(NC(=O)NSc3ccccc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.58
BCL2L1 Q07817 3/20 0.53
MCL1 Q07820 3/20 0.53
BCL2 P10415 2/20 0.53
RAB9A P51151 4/20 0.52
NPC1 O15118 3/20 0.52
LMNA P02545 2/20 0.52
KMT2A Q03164 2/20 0.50
POLB P06746 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
HTT P42858 1/20 0.50
MMP2 P08253 1/20 0.50
MMP9 P14780 1/20 0.50
MEN1 O00255 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
GFER P55789 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7770073 0.91 HSD17B10 (0.57) HSD17B10RAB9ANPC1LMNAKMT2A
SCHEMBL8768261 0.90 HSD17B10 (0.54) HSD17B10BCL2L1MCL1BCL2RAB9A
SCHEMBL6295396 0.89 KMT2A (0.50) BCL2L1MCL1BCL2LMNAKMT2A
SCHEMBL7776170 0.89 MAPT (0.51) BCL2L1MCL1RAB9ANPC1LMNA
SCHEMBL7643073 0.88 LMNA (0.60) RAB9ANPC1LMNAKMT2AMMP9
SCHEMBL8659346 0.88 HSD17B10 (0.67) HSD17B10BCL2L1MCL1RAB9ANPC1
SCHEMBL7774810 0.88 HSD17B10 (0.67) HSD17B10BCL2L1MCL1RAB9ANPC1
SCHEMBL7774533 0.87 L3MBTL1 (0.47) BCL2L1MCL1BCL2LMNAKMT2A
SCHEMBL7641936 0.85 ALDH1A1 (0.52) BCL2L1MCL1BCL2NPC1LMNA
SCHEMBL7776315 0.83 ALDH1A1 (0.48) BCL2L1MCL1BCL2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed