Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935801 | 0.94 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL7770592 | 0.87 | L3MBTL1 (0.42) | ALDH1A1LMNAL3MBTL1KDM4EHTT | |
| SCHEMBL7770589 | 0.84 | PPARG (0.41) | ALDH1A1MAPTL3MBTL1KDM4EGAA | |
| SCHEMBL8935970 | 0.84 | GRK6 (0.45) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL8934919 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL7848755 | 0.81 | PDGFRB (0.54) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL7770369 | 0.81 | PPARG (0.41) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL8935763 | 0.80 | KDR (0.37) | ALDH1A1LMNAL3MBTL1HTTMEN1 | |
| SCHEMBL8548153 | 0.79 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL7774104 | 0.77 | ADORA2A (0.43) | ALDH1A1KDM4EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248870-B1 | OLIGO-2,6-PYRIMIDINE COMPLEXING AGENT. | NYCOMED IMAGING AS (NO) | 2001-06-19 | — | — | US | disclosed |
| US-5817774-A | Unsymmetrical complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | STERLING WINTHROP INCORPORATION (US) | 1998-10-06 | — | — | US | disclosed |
| US-5559214-A | Unsymmetrical complexing agents and targeting immunoreagents useful in thearpeutic and diagnostic compositions and methods | STERLING WINTHROP INC. (US) | 1996-09-24 | — | — | US | disclosed |