Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935801 | 0.89 | ALDH1A1 (0.42) | GRK6SMN1; SMN2PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL8601997 | 0.87 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1MAPTHTTPOLB | |
| SCHEMBL30803820 | 0.84 | ADORA2A (0.37) | ALDH1A1HTTL3MBTL1LMNAABCB1 | |
| SCHEMBL7717266 | 0.84 | ADORA2A (0.37) | ALDH1A1HTTL3MBTL1LMNAABCB1 | |
| SCHEMBL7770566 | 0.84 | ALDH1A1 (0.39) | SMN1; SMN2PDGFRBPDGFRAALDH1A1MAPT | |
| SCHEMBL8936038 | 0.83 | ADORA2A (0.37) | SMN1; SMN2ALDH1A1MAPTHTTL3MBTL1 | |
| SCHEMBL8935948 | 0.82 | ADORA2A (0.36) | ALDH1A1HTTL3MBTL1LMNAMEN1 | |
| SCHEMBL8935770 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2ACYP3A4 | |
| SCHEMBL8765283 | 0.80 | MCL1 (0.45) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL9391451 | 0.80 | GYS1 (0.36) | ALDH1A1TDP1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |