Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | GLS | O94925 | 3/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 5/20 | 0.44 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307894 | 0.83 | ENPP2 (0.54) | ENPP2GLSLOXL2PNMTNOS1 | |
| SCHEMBL7769861 | 0.83 | ABAT (0.48) | LOXL2SMN1; SMN2 | |
| SCHEMBL7770968 | 0.82 | ENPP2 (0.52) | ENPP2GLSLOXL2PNMTNOS1 | |
| SCHEMBL3803115 | 0.82 | AKR1B1 (0.58) | ENPP2GLSLOXL2PNMTNOS1 | |
| Bicarbonate SCHEMBL31055574 | 0.81 | LOXL2 (0.62) | ENPP2LOXL2PNMTNOS1NOS2 | |
| SCHEMBL27550263 | 0.80 | PNMT (0.50) | ENPP2GLSLOXL2PNMTNOS1 | |
| SCHEMBL7770954 | 0.80 | BCL2 (0.46) | ALDH1A1SMN1; SMN2CYP1A2TSHRCYP2C19 | |
| SCHEMBL8105331 | 0.80 | NOS1 (0.53) | ENPP2GLSLOXL2PNMTNOS1 | |
| Hydrochloric Acid SCHEMBL3761585 | 0.80 | AKR1B1 (0.56) | ENPP2GLSLOXL2PNMTNOS1 | |
| SCHEMBL29809842 | 0.79 | PNMT (0.58) | ENPP2LOXL2PNMTNOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |