Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8235027 | 0.83 | MMP9 (0.43) | CYP2D6UTS2R | |
| SCHEMBL6656758 | 0.80 | ALDH1A1 (0.50) | CA2ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL5879436 | 0.80 | ALDH1A1 (0.50) | CA2ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL5879498 | 0.80 | ALDH1A1 (0.50) | CA2ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL7771309 | 0.79 | GHSR (0.45) | CA2ALDH1A1KMT2APTGFRKDM4E | |
| SCHEMBL8905430 | 0.79 | FCER2 (0.56) | CYP2D6 | |
| SCHEMBL6657445 | 0.77 | GHSR (0.52) | ALDH1A1KMT2APTGFRKDM4ETDP1 | |
| SCHEMBL7771304 | 0.77 | GHSR (0.52) | ALDH1A1KMT2APTGFRKDM4ETDP1 | |
| SCHEMBL18435475 | 0.76 | ALDH1A1 (0.48) | CA2ALDH1A1SMN1; SMN2KMT2ACYP1A2 | |
| SCHEMBL16252293 | 0.76 | ALDH1A1 (0.48) | CA2ALDH1A1SMN1; SMN2KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127071-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | Novo Nordisk A/S (DK) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000026252-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-05-11 | — | — | WO | disclosed |