Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FCER2 | P06734 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 6/20 | 0.50 |
| ▸ | MMP9 | P14780 | 5/20 | 0.50 |
| ▸ | MMP8 | P22894 | 5/20 | 0.50 |
| ▸ | MMP1 | P03956 | 9/20 | 0.49 |
| ▸ | MMP3 | P08254 | 5/20 | 0.48 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914696 | 0.92 | FCER2 (0.50) | FCER2MMP2MMP9MMP8MMP1 | |
| SCHEMBL8235027 | 0.87 | MMP9 (0.43) | FCER2MMP9MMP8CYP3A4CYP2D6 | |
| SCHEMBL8914878 | 0.87 | HTRA1 (0.46) | FCER2MMP2MMP9MMP8SLC6A2 | |
| SCHEMBL7132131 | 0.86 | MMP2 (0.54) | FCER2MMP2MMP9MMP8MMP1 | |
| SCHEMBL8906164 | 0.81 | CYP1A2 (0.49) | CYP3A4CYP2D6 | |
| SCHEMBL7771306 | 0.79 | CA2 (0.45) | CYP2D6 | |
| SCHEMBL20160263 | 0.75 | MMP1 (0.61) | FCER2MMP2MMP9MMP8MMP1 | |
| SCHEMBL25139614 | 0.75 | MMP1 (0.64) | FCER2MMP2MMP9MMP8MMP1 | |
| SCHEMBL13884333 | 0.75 | MMP1 (0.64) | FCER2MMP2MMP9MMP8MMP1 | |
| SCHEMBL22962378 | 0.75 | MMP1 (0.64) | FCER2MMP2MMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997023508-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-07-03 | — | — | WO | disclosed |