Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222221 | 0.82 | KMT2A (0.63) | LMNAKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL8315122 | 0.82 | ALDH1A1 (0.62) | LMNAS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL6136444 | 0.82 | LMNA (0.54) | LMNAS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL16764806 | 0.80 | KMT2A (0.49) | LMNAS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL2847121 | 0.79 | KMT2A (0.51) | LMNAKMT2AMEN1L3MBTL1SMN1; SMN2 | |
| SCHEMBL2521728 | 0.78 | CALM1 (0.51) | LMNAKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL11479099 | 0.77 | HTR1A (0.56) | LMNAS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9001844 | 0.77 | S1PR2 (0.50) | LMNAS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL5972208 | 0.77 | KDM4E (0.75) | KMT2AMEN1ATMSMN1; SMN2GAA | |
| SCHEMBL31606732 | 0.77 | KDM4E (0.75) | KMT2AMEN1ATMSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781552-B1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6011069-A | N-POLYISOPRENYL-N,N'-DIBENZYLETHYLENEDIAMINES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0781552-A1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |