SCHEMBL7773268

SCHEMBL7773268

N#Cc1ccc2nn[nH]c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 1/20 0.45
PKN1 Q16512 1/20 0.44
PKN2 Q16513 1/20 0.44
CSNK1D P48730 6/20 0.42
CSNK1A1 P48729 5/20 0.42
GSK3B P49841 4/20 0.42
CSNK1G2 P78368 4/20 0.42
METAP2 P50579 1/20 0.41
METAP1 P53582 1/20 0.41
IMPDH2 P12268 1/20 0.39
IMPDH1 P20839 1/20 0.39
NOS3 P29474 1/20 0.39
NOS1 P29475 1/20 0.39
NOS2 P35228 1/20 0.39
CHEK2 O96017 1/20 0.38
TTK P33981 1/20 0.37
ITK Q08881 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2B Q13224 1/20 0.36
CHUK O15111 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203218 0.85 IMPDH2 (0.43) PIN1PKN1PKN2CSNK1DCSNK1A1
Water SCHEMBL11184905 0.76 KMT2A (0.42) PIN1METAP2METAP1ALDH1A1
SCHEMBL29424103 0.74 KMT2A (0.43) PIN1METAP2METAP1ALDH1A1
SCHEMBL29424102 0.74 KMT2A (0.43) PIN1METAP2METAP1ALDH1A1
SCHEMBL2611832 0.74 KMT2A (0.43) PIN1METAP2METAP1ALDH1A1
Benzotriazole SCHEMBL14975700 0.73 PIK3CA (0.44) ALDH1A1
SCHEMBL16968392 0.72 ALDH1A1 (0.32) CSNK1DCSNK1G2ALDH1A1
SCHEMBL4104023 0.69 METAP2 (0.44) METAP2NOS1ALDH1A1CYP2A6
SCHEMBL735804 0.69 PRKCI (0.48) ALDH1A1
SCHEMBL12871076 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
WO-2024168426-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF APOGEE PHARMACEUTICALS, INC. (CA) 2024-08-22 WO disclosed
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-08-25 US disclosed
CN-106420754-B The purposes of benzo five-membered Azacyclyl bridged piperazine derivatives 沈阳海王生物技术有限公司 2019-11-05 CN disclosed
CN-108721289-A The purposes of benzo five-membered Azacyclyl piperidine derivative 沈阳海王生物技术有限公司 2018-11-02 CN disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
US-9802929-B2 Benzo five-membered nitrogen heterocyclic piperidine or piperazine derivatives and preparation methods and pharmaceutical compositions thereof SHENYANG HAIWANG BIOTECHNOLOGY CO., LTD. (CN) 2017-10-31 US disclosed
US-9415047-B2 Use of benzo five-membered nitrogen heterocyclic piperazine or piperidine derivatives Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) 2016-08-16 US disclosed
US-20160009703-A1 BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF LIAONING EMMY BIOLOGICAL PHARMACEUTICAL CO., LTD (CN) 2016-01-14 US disclosed
US-20150297586-A1 USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES Liaoning Emmy Biological Pharmaceutical Co., Ltd. (CN) 2015-10-22 US disclosed
EP-0897556-A1 SILVER-HALIDE RECORDING MATERIAL WITH IMPROVED STORAGE STABILITY TO PRODUCE NEGATIVES WITH ULTRAHARD-GRADATION CONTRAST Agfa-Gevaert AG (DE) 1999-02-24 EP disclosed
EP-0880059-A1 Silver halide photographic material and process for forming silver images DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1998-11-25 EP disclosed
US-5783357-A BLACK AND WHITE PHOTOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-07-21 US disclosed
EP-0740194-B1 Silver halide containing material for making negative images having ultrahigh contrast DU PONT DEUTSCHLAND (DE) 1998-04-01 EP disclosed
WO-1997042545-A1 SILVER-HALIDE RECORDING MATERIAL TO PRODUCE NEGATIVES WITH REDUCED FOG AND ULTRAHARD-GRADATION AGFA-GEVAERT AG (DE) 1997-11-13 WO disclosed
WO-1997042546-A1 SILVER-HALIDE RECORDING MATERIAL WITH IMPROVED STORAGE STABILITY TO PRODUCE NEGATIVES WITH ULTRAHARD-GRADATION CONTRAST AGFA-GEVAERT AG (DE) 1997-11-13 WO disclosed
EP-0618491-B1 Method for generation of negative images having ultrahigh contrast DU PONT DEUTSCHLAND (DE) 1997-08-27 EP disclosed
EP-0740194-A1 Silver halide containing material for making negative images having ultrahigh contrast DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1996-10-30 EP disclosed
EP-0733939-A1 Siver halide recording material for generation of negative images with ultrahigh contrast DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1996-09-25 EP disclosed
EP-0618491-A1 Method for generation of negative images having ultrahigh contrast DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1994-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10756394-B2 Nonaqueous electrolyte and nonaqueous secondary battery BPTF, BRD4, KCNN2 PIN1 1914/4885PKN1 1658/4885PKN2 515/4885
US-20150297586-A1 USE OF BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERAZINE OR PIPERIDINE DERIVATIVES P2RX5, TBXA2R, CYP3A5 PIN1 2991/4885PKN1 1458/4885PKN2 981/4885
US-20160009703-A1 BENZO FIVE-MEMBERED NITROGEN HETEROCYCLIC PIPERIDINE OR PIPERAZINE DERIVATIVES AND PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS THEREOF CYP3A5, IL5, ABCC5 PIN1 2541/4885PKN1 1347/4885PKN2 602/4885
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 PIN1 1914/4885PKN1 1658/4885PKN2 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.