SCHEMBL203218

SCHEMBL203218

N#Cc1ccc2[nH]nnc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.43
IMPDH1 P20839 1/20 0.43
CHUK O15111 1/20 0.39
PIN1 Q13526 1/20 0.38
PKN1 Q16512 1/20 0.37
PKN2 Q16513 1/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
GABRA2 P47869 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37
GABRE P78334 1/20 0.37
GABRA6 Q16445 1/20 0.37
GABRG1 Q8N1C3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773268 0.85 PIN1 (0.45) IMPDH2IMPDH1CHUKPIN1PKN1
SCHEMBL23348979 0.84 HAO1 (0.35)
SCHEMBL26790059 0.81 HAO1 (0.36) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL26790062 0.75 GABRA1 (0.36) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL6152208 0.74 MAPT (0.43) ALDH1A1
Benzotriazole SCHEMBL14975700 0.73 PIK3CA (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL19640293 0.73 CLK1 (0.34) GSK3B
SCHEMBL16968392 0.72 ALDH1A1 (0.32) CSNK1DCSNK1G2KDM4EALDH1A1
Water SCHEMBL7451096 0.72 ALDH1A1 (0.47) KDM4EALDH1A1GAA
SCHEMBL23348984 0.71 CLK1 (0.37) GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119461335-B Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-03-18 CN claimed
CN-119461335-A Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-02-18 CN claimed
CN-113589662-B Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2022-07-12 CN claimed
CN-113589662-A Composition, stripping liquid, application of stripping liquid in stripping of photoresist or photoresist residues and stripping method 浙江奥首材料科技有限公司 2021-11-02 CN claimed
EP-4665718-A1 SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF Apogee Pharmaceuticals, Inc. (CA) 2025-12-24 EP disclosed
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof APOGEE PHARMACEUTICALS, INC. (CA) 2025-08-05 US disclosed
CN-119461335-B Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-03-18 CN disclosed
CN-119461335-B Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-03-18 CN disclosed
CN-119461335-A Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-02-18 CN disclosed
CN-119461335-A Low-temperature-resistant composite material, preparation method and application thereof in lithium ion battery anode material 深圳市量能科技有限公司 2025-02-18 CN disclosed
US-20250026742-A1 COMPOUND AS ATR KINASE INHIBITOR SUZHOU ARK BIOPHARMACEUTICAL CO., LTD. (CN) 2025-01-23 US disclosed
CN-115703768-B Compounds useful as inhibitors of ATR kinase 苏州爱科百发生物医药技术有限公司 2024-12-17 CN disclosed
US-5320938-A Occurs in the presence of iodide EASTMAN KODAK COMPANY (US) 1994-06-14 US disclosed
US-5288596-A Developing with solution containing imidazole compound and benzotriazole compound FUJI PHOTO FILM CO., LTD. (JP) 1994-02-22 US disclosed
EP-0554000-A1 A black-and-white silver halide photographic light-sensitive material and a method for processing the same KONICA CORPORATION (JP) 1993-08-04 EP disclosed
EP-0545645-A1 Solid processing chemicals for light-sensitive halide photographic material KONICA CORPORATION (JP) 1993-06-09 EP disclosed
EP-0523721-A1 Black and white direct positive image forming process FUJI PHOTO FILM CO., LTD. (JP) 1993-01-20 EP disclosed
US-H1020-H Developing solution containing an antifogging agent of a benzotriazole or benzimidazole and a thioether compound KONICA CORPORATION (JP) 1992-02-04 US disclosed
EP-0358165-A2 Method of developing a silver halide photographic material KONICA CORPORATION (JP) 1990-03-14 EP disclosed
US-4649096-A EXPOSURE, DEVELOPMENT, ALKALI HYDROXIDE, ALKANOLAMINE, SULFITE, THIOSULFATE, P-DIHYDROXYBENZENE MITSUBISHI PAPER MILLS, LTD. (JP) 1987-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026742-A1 COMPOUND AS ATR KINASE INHIBITOR ATR, CHEK2, CHEK1 IMPDH2 2146/4885IMPDH1 1621/4885CHUK 228/4885
US-12378231-B2 Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof MGLL, PNLIP, LPL IMPDH2 1576/4885IMPDH1 1247/4885CHUK 2489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.