Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7775560 | 0.87 | ALDH1A1 (0.41) | P2RX7ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7773719 | 0.87 | P2RX7 (0.47) | P2RX7ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7775646 | 0.86 | OPRD1 (0.46) | P2RX7DRD2DRD3DRD4 | |
| SCHEMBL7098294 | 0.81 | DRD2 (0.42) | P2RX7ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7097689 | 0.78 | DRD3 (0.60) | DRD2DRD3DRD4 | |
| SCHEMBL7097673 | 0.78 | DRD3 (0.60) | DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7775567 | 0.73 | OPRD1 (0.49) | DRD2DRD3DRD4 | |
| SCHEMBL7103907 | 0.72 | DRD2 (0.42) | P2RX7ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL7773713 | 0.72 | DRD2 (0.52) | P2RX7DRD2DRD3DRD4 | |
| SCHEMBL7097627 | 0.69 | DRD3 (0.59) | DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690051-B1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | AZWELL INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-0690051-A1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |