SCHEMBL77781

SCHEMBL77781

NCCc1ccc(S(=O)(=O)F)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 1.00
TMPRSS4 Q9NRS4 2/20 1.00
CYP1A2 P05177 2/20 1.00
TP53 P04637 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
CA2 P00918 3/20 0.67
CA12 O43570 2/20 0.67
CA1 P00915 2/20 0.67
CA4 P22748 2/20 0.67
CA6 P23280 2/20 0.67
CA5A P35218 2/20 0.67
CA7 P43166 2/20 0.67
CA9 Q16790 2/20 0.67
CA14 Q9ULX7 2/20 0.67
CA5B Q9Y2D0 2/20 0.67
HTR6 P50406 3/20 0.60
TAAR1 Q96RJ0 8/20 0.52
CYP2A6 P11509 2/20 0.46
HTR2A P28223 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL25973 0.98 F2 (1.00) F2TMPRSS4CYP1A2TP53CYP2D6
Hydrochloric Acid SCHEMBL6425431 0.98 F2 (1.00) F2TMPRSS4CYP1A2TP53CYP2D6
Hydrochloric Acid SCHEMBL28825226 0.96 F2 (0.96) F2TMPRSS4CYP1A2TP53CYP2D6
Hydrochloric Acid SCHEMBL723369 0.96 F2 (0.92) F2TMPRSS4CYP1A2TP53CYP2D6
Hypochlorous Acid SCHEMBL17004810 0.94 F2 (0.89) F2TMPRSS4CYP1A2TP53CYP2D6
SCHEMBL31631413 0.83 F2 (0.71) F2TMPRSS4CYP1A2TP53CYP2D6
SCHEMBL6680951 0.82 HTR6 (0.84) F2TMPRSS4CYP1A2TP53CYP2D6
Benzamidine SCHEMBL3427811 0.81 F2 (0.66) F2TMPRSS4CYP1A2TP53CYP2D6
Hydrochloric Acid SCHEMBL21199324 0.80 F2 (0.70) F2TMPRSS4CYP1A2TP53CYP2D6
SCHEMBL142107 0.80 CA2 (1.00) F2TMPRSS4CYP1A2TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4372 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122081365-A Alpha-hemolysin recombinant protein and prokaryotic expression method thereof 2026-05-26 CN claimed
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
US-20260125640-A1 ACELLULAR PLACENTAL PREPARATIONS PLAKOUS THERAPEUTICS INC (US) 2026-05-07 US claimed
US-12584161-B2 Stabilization of nucleic acids in urine STRECK LLC (US) 2026-03-24 US claimed
US-20260041663-A1 PREVENTION OF ROSACEA INFLAMMATION UNIV CALIFORNIA (US) 2026-02-12 US claimed
EP-4662310-A2 METHODS AND KITS FOR LABELING CELLULAR MOLECULES FOR MULTIPLEX ANALYSIS Parse Biosciences, Inc. (US) 2025-12-17 EP claimed
US-12453346-B2 Stabilization of whole blood at room temperature ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2025-10-28 US claimed
US-20250281579-A1 Methods and Compositions for Oral Administration of Proteins ORAMED PHARMACEUTICALS INC (IL) 2025-09-11 US claimed
US-12383554-B2 Compositions and methods to protect mammalian tissue against cold and other metabolic stresses THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2025-08-12 US claimed
EP-4008400-B1 ACELLULAR PLACENTAL PREPARATIONS PLAKOUS THERAPEUTICS INC (US) 2025-06-18 EP claimed
EP-1221948-A2 USE OF COMPOSITIONS FOR THE CARING TREATMENT OF THE SKIN Henkel Kommanditgesellschaft auf Aktien (DE) 2002-07-17 EP claimed
WO-2002030453-A1 METHODS OF INHIBITING ANGIOGENESIS USING NADPH OXIDASE INHIBITORS BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2002-04-18 WO claimed
US-20020018802-A1 Wound coverings for removal of interfering factors from wound fluid MEYER-INGOLD WOLFGANG (DE) 2002-02-14 US claimed
US-20020012958-A1 INCREASING THE FVII SENSITIVITY OF A THROMBOPLASTIN REAGENT DADE BEHRING MARBURG GMBH (DE) 2002-01-31 US claimed
WO-2001089449-A2 PHOSPHOLIPASE D EFFECTORS FOR THERAPY AND SCREENING WILLIGER BEN (IL) 2001-11-29 WO claimed
WO-2001028536-A2 USE OF COMPOSITIONS FOR THE CARING TREATMENT OF THE SKIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-04-26 WO claimed
WO-2001029163-A1 CLEANING AGENTS WHICH CONTAIN SURFACTANTS AND ENZYME INHIBITORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-04-26 WO claimed
EP-0945144-A2 Wound dressing for removal of interference factors from wound exudate Beiersdorf Aktiengesellschaft (DE) 1999-09-29 EP claimed
EP-0878551-A2 Enhancement of the factor-VII sensitivity of a thromboplastin reagent Dade Behring Marburg GmbH (DE) 1998-11-18 EP claimed
WO-1994016082-A1 X-PROLYL-DIPEPTIDYL-AMINOPEPTIDASE FROM LACTOBACILLUS DELBRÜCKII SSP. LACTIS, NUCLEIC ACIDS CODING FOR THE SAME AND ITS USE IN FERMENTED FOODSTUFF PREPARATION PROCESSES COMMUNAUTE ECONOMIQUE EUROPEENNE (CEE) (LU) 1994-07-21 WO claimed