SCHEMBL7778378

SCHEMBL7778378

Cc1ccc(C(=O)[N]C(N)=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
TDP1 Q9NUW8 3/20 0.45
PKM P14618 2/20 0.45
HTT P42858 2/20 0.45
ATM Q13315 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HPGD P15428 1/20 0.45
NLRP1 Q9C000 1/20 0.45
GAA P10253 1/20 0.45
MEN1 O00255 1/20 0.45
NTSR1 P30989 1/20 0.45
KMT2A Q03164 1/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691184 0.86 ALDH1A1 (0.59) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL4435595 0.78 TPH1 (0.51) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL1750474 0.77 TDP1 (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL4269458 0.75 ALDH1A1 (0.56) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL13536412 0.75 ALDH1A1 (0.56) ALDH1A1CES2CES1LMNASMN1; SMN2
Terephthalamide SCHEMBL17907469 0.74 ALDH1A1 (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL76475 0.74 ALDH1A1 (0.62) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL16358251 0.73 ALDH1A1 (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2
SCHEMBL163160 0.73 HTR3E (0.54) ALDH1A1CES2CES1LMNASMN1; SMN2
P-Xylene SCHEMBL28147896 0.72 ALDH1A1 (0.58) ALDH1A1CES2CES1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1145078-A1 PHOTOGRAPHIC COUPLERS HAVING IMPROVED IMAGE DYE LIGHT STABILITY EASTMAN KODAK COMPANY (US) 2001-10-17 EP disclosed
WO-2000038013-A1 PHOTOGRAPHIC COUPLERS HAVING IMPROVED IMAGE DYE LIGHT STABILITY EASTMAN KODAK COMPANY (US) 2000-06-29 WO disclosed