Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7777487 | 0.90 | TSHR (0.32) | RAB9AALDH1A1 | |
| SCHEMBL7778620 | 0.89 | RAB9A (0.34) | RAB9AALDH1A1 | |
| SCHEMBL7777489 | 0.86 | GAA (0.35) | RAB9AALDH1A1 | |
| SCHEMBL7771284 | 0.78 | HSD17B10 (0.34) | RAB9AALDH1A1 | |
| SCHEMBL7778659 | 0.76 | CYP1A2 (0.35) | — | |
| SCHEMBL7778629 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL7777366 | 0.75 | NAAA (0.38) | ALDH1A1 | |
| SCHEMBL7775615 | 0.74 | ALDH1A1 (0.34) | RAB9AALDH1A1 | |
| SCHEMBL7775623 | 0.74 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL12565684 | 0.74 | RAB9A (0.44) | RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733045-B1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| US-5880130-A | TREATMENT OF CELL-PROLIFERATION DISEASES | ZENECA LIMITED (GB) | 1999-03-09 | — | — | US | disclosed |