Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5050115 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E | |
| Hydrochloric Acid SCHEMBL9869331 | 0.98 | ALDH1A1 (0.49) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E | |
| SCHEMBL11603748 | 0.89 | ALDH1A1 (0.54) | ALDH1A1CYP2D6KDM4ECTDSP1KMT2A | |
| SCHEMBL5053504 | 0.88 | ADRA2A (0.43) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E | |
| SCHEMBL7784242 | 0.88 | ADRA2A (0.43) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E | |
| SCHEMBL6055190 | 0.85 | ALOX15 (0.51) | ALDH1A1CYP2D6KDM4ECTDSP1KMT2A | |
| SCHEMBL147185 | 0.85 | ALDH1A1 (0.55) | ALDH1A1ADRA2ACYP2D6KDM4EADRA2C | |
| SCHEMBL9633340 | 0.84 | ALDH1A1 (0.47) | ALDH1A1CYP2D6KDM4ECTDSP1KMT2A | |
| SCHEMBL8782512 | 0.83 | LIPE (0.49) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E | |
| SCHEMBL7786253 | 0.83 | ADRA2A (0.64) | ALDH1A1ADRA2ACYP2D6ADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |