Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633328 | 0.88 | CYP2D6 (0.42) | L3MBTL1KDM4EKMT2ATDP1MAPK1 | |
| SCHEMBL11603748 | 0.87 | ALDH1A1 (0.54) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL7779145 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL5050115 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| Hydrochloric Acid SCHEMBL9869331 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL6055190 | 0.80 | ALOX15 (0.51) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL12261507 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL9632245 | 0.79 | ADRA2A (0.45) | KDM4EKMT2ATDP1MAPK1CYP2D6 | |
| SCHEMBL11603876 | 0.79 | L3MBTL1 (0.49) | ALDH1A1CTDSP1ALOX15L3MBTL1GLA | |
| SCHEMBL9203944 | 0.78 | KDM4E (0.43) | ALDH1A1KDM4ETDP1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145998-A | Reduction of oxime or silyloxime | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-09-08 | — | — | US | disclosed |
| EP-0237305-B1 | A METHOD FOR PRODUCING OPTICALLY ACTIVE AMINES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |