Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6913749 | 0.85 | CTSV (0.45) | CTSVCTSLMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7111021 | 0.84 | CTSV (0.44) | CTSVCTSLMEN1KMT2APOLB | |
| SCHEMBL7778742 | 0.81 | CTSV (0.42) | CTSVCTSLGABRA1GABRG2GABRB3 | |
| SCHEMBL7781279 | 0.77 | KIF11 (0.39) | CTSVCTSLMEN1KMT2AHTR1A | |
| SCHEMBL7778756 | 0.76 | CTSV (0.38) | CTSVCTSLMAOAADRA1A | |
| SCHEMBL6911186 | 0.76 | ADRB3 (0.51) | CTSVCTSLADRA1A | |
| SCHEMBL6911409 | 0.75 | ADRB2 (0.51) | CTSVCTSLMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7106190 | 0.75 | ADRB3 (0.50) | CTSVCTSLADRA1A | |
| SCHEMBL7113210 | 0.75 | CTSV (0.43) | CTSVCTSLMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL7110487 | 0.74 | ADRB2 (0.51) | CTSVCTSLMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128845-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTDIABETIC AGENT | SMITHKLINE BEECHAM PLC (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027434-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTIDIABETIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |