Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780041 | 1.00 | MEN1 (0.38) | MEN1KMT2ATHRBPOLBCES2 | |
| SCHEMBL5860474 | 0.94 | MEN1 (0.40) | MEN1KMT2ATHRBPOLBCES2 | |
| SCHEMBL997304 | 0.79 | ALDH1A1 (0.49) | MEN1KMT2ATHRBPKMMAPT | |
| SCHEMBL5205743 | 0.77 | PKM (0.45) | MEN1KMT2APKMMAPTLMNA | |
| SCHEMBL7749609 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2ATHRBPOLBPKM | |
| SCHEMBL15059313 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2ATHRBPOLBPKM | |
| Malonic Acid Diethyl Ester SCHEMBL5861514 | 0.76 | THRB (0.45) | THRBPOLBHTTMAPTLMNA | |
| SCHEMBL7750957 | 0.76 | ALDH1A1 (0.42) | MEN1KMT2ATHRBPOLBPKM | |
| SCHEMBL15577402 | 0.75 | MAPT (0.38) | MEN1KMT2APOLBPKMMAPT | |
| SCHEMBL396111 | 0.75 | MAPT (0.47) | MEN1KMT2APKMHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |