SCHEMBL7780123

SCHEMBL7780123

Cc1c(OC(=O)Cl)ccc2c1C(=O)N(C)S2(=O)=O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
ELANE P08246 3/20 0.33
ABCC9 O60706 1/20 0.32
ABCC8 Q09428 1/20 0.32
KCNJ11 Q14654 1/20 0.32
KCNJ8 Q15842 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
HSD11B1 P28845 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7779967 0.89 CA2 (0.38) CA2CA9ELANEABCC9ABCC8
SCHEMBL6971918 0.67 POLB (0.30) POLB
SCHEMBL7813152 0.60 CXCR2 (0.42)
SCHEMBL8463126 0.60 POLB (0.56) POLBMAPT
SCHEMBL6972568 0.59 HDAC4 (0.31)
SCHEMBL19979062 0.59 MRGPRX4 (0.47) POLBMAPT
SCHEMBL6587153 0.58 POLB (0.39) POLBMAPT
SCHEMBL8466385 0.57 L3MBTL1 (0.50) MAPT
SCHEMBL6982130 0.56 RYR2 (0.32)
SCHEMBL22023812 0.56 LMNA (0.35) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775124-B1 HERBICIDAL SACCHARIN CARBOXYLIC ACID DERIVATIVES AND METHOD FOR THEIR PREPARATION BASF AG (DE) 2001-09-19 EP disclosed