SCHEMBL7813152

SCHEMBL7813152

Cc1c(OC(=O)Cl)ccc2c1S(=O)(=O)CCC2=O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.42
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7813962 0.79 CXCR2 (0.40) CXCR2
SCHEMBL6971918 0.77 POLB (0.30)
SCHEMBL8596112 0.75 CXCR2 (0.44) CXCR2
SCHEMBL7992005 0.74 CXCR2 (0.46) CXCR2KDM4E
SCHEMBL6972568 0.72 HDAC4 (0.31)
SCHEMBL23446590 0.69 CXCR2 (0.51) CXCR2ALDH1A1
SCHEMBL8166451 0.68 CXCR2 (0.41) CXCR2
SCHEMBL23446596 0.63 CXCR2 (0.48) CXCR2ALDH1A1
SCHEMBL7815909 0.62 KDM4E (0.36) KDM4EALDH1A1HPGD
SCHEMBL7780123 0.60 CA2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0961774-B1 PYRAZOL-4-YL-BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AG (DE) 2001-12-12 EP disclosed
EP-0961774-A1 PYRAZOL-4-YL-BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-12-08 EP disclosed
EP-0847394-A1 2-CYCLOHEXANE-1,3-DIONE BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1998-06-17 EP disclosed
WO-1997009324-A1 2-CYCLOHEXANE-1,3-DIONE BENZOYL DERIVATIVES BASF AKTIENGESELLSCHAFT (DE) 1997-03-13 WO disclosed
WO-1997009327-A1 PYRAZOL-4-YL-BENZOYL DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1997-03-13 WO disclosed