Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7815909 | 0.84 | KDM4E (0.36) | — | |
| SCHEMBL7813152 | 0.77 | CXCR2 (0.42) | — | |
| SCHEMBL7624166 | 0.76 | RYR2 (0.30) | — | |
| SCHEMBL6972568 | 0.76 | HDAC4 (0.31) | — | |
| SCHEMBL7780123 | 0.67 | CA2 (0.36) | POLB | |
| SCHEMBL7474688 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL6981392 | 0.63 | RXRA (0.33) | — | |
| SCHEMBL8463126 | 0.63 | POLB (0.56) | POLB | |
| SCHEMBL19979062 | 0.61 | MRGPRX4 (0.47) | POLB | |
| SCHEMBL7620956 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080089-B1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AG (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1080089-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999059991-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |