Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787602 | 0.92 | ALDH1A1 (0.44) | TDP1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7785046 | 0.87 | TDP1 (0.49) | TDP1KMT2AALDH1A1GAAHTT | |
| SCHEMBL7780362 | 0.83 | TDP1 (0.50) | TDP1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7789152 | 0.81 | SIGMAR1 (0.53) | TDP1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7780342 | 0.79 | KMT2A (0.54) | TDP1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL7785129 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7785574 | 0.78 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7787461 | 0.77 | TDP1 (0.55) | TDP1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL7785644 | 0.76 | RAB9A (0.47) | KMT2AALDH1A1GAAMAPTSMN1; SMN2 | |
| SCHEMBL7787942 | 0.76 | TDP1 (0.49) | TDP1KMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |