Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785084 | 0.92 | CRHBP (0.47) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7780324 | 0.92 | CRHBP (0.47) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7780656 | 0.92 | ALDH1A1 (0.47) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL27540196 | 0.90 | ACP3 (0.50) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7785642 | 0.90 | ACP3 (0.50) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7785688 | 0.90 | CRHBP (0.44) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7785576 | 0.90 | CRHBP (0.44) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7785105 | 0.90 | CRHBP (0.44) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7787888 | 0.90 | ALDH1A1 (0.47) | CRHBPCRHR2ACP3KMT2AMEN1 | |
| SCHEMBL7785144 | 0.87 | AKR1C3 (0.48) | CRHBPCRHR2ACP3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |