Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780401 | 0.92 | CRHBP (0.53) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7780378 | 0.89 | MAPK1 (0.46) | ALDH1A1HTTKMT2AMEN1ACP3 | |
| SCHEMBL7785099 | 0.86 | AKR1C3 (0.43) | ALDH1A1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL7785084 | 0.85 | CRHBP (0.47) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7780324 | 0.85 | CRHBP (0.47) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7785642 | 0.83 | ACP3 (0.50) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL27540196 | 0.83 | ACP3 (0.50) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7787888 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7785688 | 0.82 | CRHBP (0.44) | ALDH1A1CRHBPCRHR2HTTGAA | |
| SCHEMBL7785105 | 0.82 | CRHBP (0.44) | ALDH1A1CRHBPCRHR2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |