Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780401 | 0.90 | CRHBP (0.53) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7780425 | 0.86 | MAPK1 (0.46) | ALDH1A1HTTLMNATSHRTDP1 | |
| SCHEMBL7780324 | 0.85 | CRHBP (0.47) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7785084 | 0.85 | CRHBP (0.47) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL27540196 | 0.83 | ACP3 (0.50) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7785642 | 0.83 | ACP3 (0.50) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7780656 | 0.82 | ALDH1A1 (0.47) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7785144 | 0.81 | AKR1C3 (0.48) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7785688 | 0.80 | CRHBP (0.44) | ALDH1A1HTTGAACRHBPCRHR2 | |
| SCHEMBL7788967 | 0.80 | MAPK1 (0.51) | ALDH1A1HTTLMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |