Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15379086 | 0.86 | PARP1 (0.49) | NPSR1KEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL28991119 | 0.79 | AKR1B1 (0.43) | POLBADRA1AMEN1KMT2A | |
| SCHEMBL17605074 | 0.76 | FFAR1 (0.47) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3652088 | 0.74 | POLB (0.51) | NPSR1KEAP1POLBFFAR1MAPK1 | |
| SCHEMBL4336097 | 0.73 | KEAP1 (0.54) | NPSR1KEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL30403428 | 0.73 | KEAP1 (0.54) | NPSR1KEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL16124423 | 0.73 | PCNA (0.63) | POLBFFAR1MAPK1ADRA1ASMN1; SMN2 | |
| SCHEMBL10711638 | 0.72 | LMNA (0.49) | NPSR1POLBPTGER1PTGER4PTGER3 | |
| SCHEMBL5429266 | 0.72 | FFAR1 (0.49) | NPSR1POLBGPR17FFAR1HDAC6 | |
| SCHEMBL7317838 | 0.72 | FFAR1 (0.45) | NPSR1POLBGPR17FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588869-B1 | X-RAY CONTRAST AGENT | SCOTIA LIPIDTEKNIK AB (SE) | 1999-10-13 | — | — | EP | claimed |
| US-5550263-A | PHOSPHOLIPID TO WHICH X-RAY CONTRAST AGENT HAS BEEN COVALENTLY LINKED BY ESTER OR AMIDE BOND | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1996-08-27 | — | — | US | claimed |
| EP-0588869-A1 | X-RAY CONTRAST AGENT | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1994-03-30 | — | — | EP | claimed |
| WO-1992021384-A1 | X-RAY CONTRAST AGENT | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1992-12-10 | — | — | WO | claimed |
| EP-1133346-A1 | A PROCESS FOR THE RECOVERY OF IODINE FROM AQUEOUS SOLUTIONS CONTAINING IODINATED ORGANIC COMPOUNDS | Bracco Imaging S.p.A. (IT) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000032303-A1 | A PROCESS FOR THE RECOVERY OF IODINE FROM AQUEOUS SOLUTIONS CONTAINING IODINATED ORGANIC COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2000-06-08 | — | — | WO | disclosed |
| EP-0588869-B1 | X-RAY CONTRAST AGENT | SCOTIA LIPIDTEKNIK AB (SE) | 1999-10-13 | — | — | EP | disclosed |
| US-5550263-A | PHOSPHOLIPID TO WHICH X-RAY CONTRAST AGENT HAS BEEN COVALENTLY LINKED BY ESTER OR AMIDE BOND | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1996-08-27 | — | — | US | disclosed |
| EP-0703790-A1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO S.p.A. (IT) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994027644-A1 | IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS | BRACCO S.P.A. (IT) | 1994-12-08 | — | — | WO | disclosed |
| EP-0588869-A1 | X-RAY CONTRAST AGENT | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1994-03-30 | — | — | EP | disclosed |
| WO-1992021384-A1 | X-RAY CONTRAST AGENT | KARLSHAMNS LIPIDTEKNIK AB (SE) | 1992-12-10 | — | — | WO | disclosed |