Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6053373 | 0.81 | RXFP1 (0.46) | RXFP1KMT2ACASP6ALDH1A1HPGD | |
| SCHEMBL29230461 | 0.78 | ALDH1A1 (0.53) | KMT2AALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL1900214 | 0.78 | RXFP1 (0.66) | RXFP1KMT2AMEN1CASP6ALDH1A1 | |
| SCHEMBL30842828 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDKDM4EMAPTMAOA | |
| Acetic Acid SCHEMBL4438549 | 0.72 | WDR5 (0.49) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL8982554 | 0.72 | KDM4E (0.63) | RXFP1KMT2AMEN1CASP6ALDH1A1 | |
| SCHEMBL14596146 | 0.72 | CYP3A4 (0.39) | RXFP1KMT2AMEN1 | |
| SCHEMBL25946008 | 0.72 | RXFP1 (0.80) | RXFP1KMT2AMEN1CASP6ALDH1A1 | |
| SCHEMBL30881878 | 0.72 | RXFP1 (0.80) | RXFP1KMT2AMEN1CASP6ALDH1A1 | |
| SCHEMBL357522 | 0.71 | KDM4E (0.69) | RXFP1KMT2AMEN1CASP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258967-B2 | Process for producing optically active alcohols | TAKASAGO PERFUMERY CO LTD (JP) | 1996-08-21 | — | — | EP | claimed |
| EP-0245960-B1 | PROCESS FOR PREPARING N-ACYLTETRAHYDROISOQUINOLINE | Takasago Perfumery Co., Ltd. (JP) | 1992-07-29 | — | — | EP | claimed |
| EP-0272787-B1 | CATALYTIC PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID | Takasago International Corporation (JP) | 1992-05-06 | — | — | EP | claimed |
| US-4962230-A | RUTHENIUM-OPTICALLY ACTIVE PHOSPHINE COMPLEX HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1990-10-09 | — | — | US | claimed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | claimed |
| EP-0272787-A2 | Catalytic production of optically active carboxylic acid | Takasago International Corporation (JP) | 1988-06-29 | — | — | EP | claimed |
| EP-0258967-A2 | Process for producing optically active alcohols | Takasago Perfumery Co., Ltd. (JP) | 1988-03-09 | — | — | EP | claimed |
| EP-0855390-B1 | A process for producing optically active pyrrolidine derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-5942629-A | HYDROGENATING 3-ACETYL-1-BENZYL-2-PYRROLIDINONE IN PRESENCE OF A COMPLEX FORMED FROM BIDENTATE PHOSPHINE AND RUTHENIUM CATALYST TO PRODUCE INTERMEDIATE, REDUCING THE INTERMEDIATE, MESYLATING OR TOSYLATING THE PRODUCT, FINALLY METHYLAMINATING | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0855390-A1 | A process for producing optically active pyrrolidine derivatives | Takasago International Corporation (JP) | 1998-07-29 | — | — | EP | disclosed |
| US-5587510-A | ASYMMETRICAL HYDROGENATION USING RUTHENIUM-PHOPSHINE COMPLEX AS CATALYSTS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0258967-B2 | Process for producing optically active alcohols | TAKASAGO PERFUMERY CO LTD (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5204460-A | Reacting azetidinone compound with acetic acid and oxidizing agent in the presence of ruthenium catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1993-04-20 | — | — | US | disclosed |
| EP-0272787-B1 | CATALYTIC PRODUCTION OF OPTICALLY ACTIVE CARBOXYLIC ACID | Takasago International Corporation (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4851537-A | Process for preparing N-acyltetrahydroisoquinoline | TAKASAGO PERFUMERY CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0272787-A2 | Catalytic production of optically active carboxylic acid | Takasago International Corporation (JP) | 1988-06-29 | — | — | EP | disclosed |
| EP-0258967-A2 | Process for producing optically active alcohols | Takasago Perfumery Co., Ltd. (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4705895-A | METAL COMPLEXES AS ASYMMETRIC SYNTHESES | TAKASAGO PERFUMERY CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| US-4705895-A | METAL COMPLEXES AS ASYMMETRIC SYNTHESES | TAKASAGO PERFUMERY CO., LTD. (JP) | 1987-11-10 | — | — | US | disclosed |
| EP-0235450-A1 | Phosphine compounds for complex catalysts for asymmetric syntheses | Takasago Perfumery Co., Ltd. (JP) | 1987-09-09 | — | — | EP | disclosed |