Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1847688 | 0.91 | GABRG2 (0.37) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL1845591 | 0.90 | KDM4E (0.43) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7488070 | 0.85 | ALDH1A1 (0.33) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23800896 | 0.85 | SLC16A3 (0.41) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29565491 | 0.85 | SLC16A3 (0.41) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7782083 | 0.85 | KDM4E (0.44) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13868624 | 0.83 | KDM4E (0.35) | SLC16A3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5645606 | 0.82 | MAPT (0.35) | ALDH1A1HPGDSMN1; SMN2MAPTRAB9A | |
| SCHEMBL7936515 | 0.81 | KEAP1 (0.42) | SLC16A3KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL1848196 | 0.81 | PLA2G2A (0.41) | MAOAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248264-B1 | WINDOWS OR EYEGLASS/SUNGLASS LENSES HAVING GOOD DARKENING AND LIGHTENING PERFORMANCE WITH HIGH OPTICAL DENSITY | JAMES ROBINSON LIMITED (GB) | 2001-06-19 | — | — | US | disclosed |
| EP-0971914-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2$i(H)-NAPHTHO 1,2-$i(b)]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998042693-A2 | NEUTRAL COLOURING PHOTOCHROMIC 2H-NAPHTHO[1,2-b]PYRANS AND HETEROCYCLIC PYRANS | JAMES ROBINSON LIMITED (GB) | 1998-10-01 | — | — | WO | disclosed |