SCHEMBL7782559

SCHEMBL7782559

C=CC(=O)NCc1ccc(S(=O)(=O)NS(=O)(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
TGM2 P21980 1/20 0.48
CYP19A1 P11511 1/20 0.47
NPY5R Q15761 2/20 0.46
NPY1R P25929 1/20 0.44
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 2/20 0.43
CTSS P25774 1/20 0.43
BDKRB1 P46663 2/20 0.43
BDKRB2 P30411 1/20 0.43
TPSAB1 Q15661 1/20 0.43
TBXA2R P21731 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
FGB P02675 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
PABPC1 P11940 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397718 0.88 LMNA (0.56) POLBTGM2ALDH1A1MEN1KMT2A
SCHEMBL398955 0.88 HDAC1 (0.57) POLBTGM2ALDH1A1MEN1KMT2A
SCHEMBL7785815 0.87 TGM2 (0.55) TGM2ALDH1A1MEN1KMT2A
SCHEMBL8475006 0.81 TGM2 (0.57) TGM2ALDH1A1TPSAB1MEN1KMT2A
SCHEMBL7784363 0.81 ALDH1A1 (0.54) POLBTGM2ALDH1A1MEN1KMT2A
SCHEMBL397573 0.79 AKR1C3 (0.56) CYP19A1F2F10ALDH1A1MEN1
SCHEMBL9568696 0.79 ALDH1A1 (0.59) POLBCYP19A1NPY5RNPY1RL3MBTL1
SCHEMBL14607474 0.77 L3MBTL1 (0.54) F2L3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL396803 0.77 RECQL (0.57) TGM2ALDH1A1MEN1KMT2AMAPT
SCHEMBL396618 0.77 ALDH1A1 (0.56) TGM2ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed