SCHEMBL14607474

SCHEMBL14607474

C=CC(=O)NS(=O)(=O)c1ccc2ccccc2c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.54
HDAC1 Q13547 1/20 0.53
KAT6A Q92794 7/20 0.51
LARS1 Q9P2J5 1/20 0.51
F2 P00734 1/20 0.50
PRSS1 P07477 1/20 0.50
PRSS2 P07478 1/20 0.50
PRSS3 P35030 1/20 0.50
BCL2L1 Q07817 1/20 0.50
MCL1 Q07820 1/20 0.50
RAPGEF3 O95398 1/20 0.49
ALDH1A1 P00352 2/20 0.49
LMNA P02545 2/20 0.49
GAA P10253 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
NLRP3 Q96P20 1/20 0.48
SLC1A3 P43003 1/20 0.48
SLC1A2 P43004 1/20 0.48
SLC1A1 P43005 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568833 0.82 SLC1A3 (0.50) L3MBTL1HDAC1KAT6ALARS1F2
SCHEMBL11032473 0.82 L3MBTL1 (0.62) L3MBTL1KAT6ALARS1F2PRSS1
SCHEMBL9568696 0.80 ALDH1A1 (0.59) L3MBTL1KAT6AALDH1A1LMNAGAA
SCHEMBL9568645 0.80 HDAC1 (0.62) HDAC1ALDH1A1LMNAGAASMN1; SMN2
SCHEMBL7610253 0.80 L3MBTL1 (0.61) L3MBTL1KAT6ALARS1F2PRSS1
SCHEMBL7774671 0.80 L3MBTL1 (0.61) L3MBTL1KAT6ALARS1F2PRSS1
SCHEMBL962549 0.80 CA2 (0.55) L3MBTL1HDAC1LMNAMEN1KMT2A
SCHEMBL29644482 0.79 KAT6A (0.73) L3MBTL1KAT6ABCL2L1MCL1ALDH1A1
SCHEMBL3267159 0.79 L3MBTL1 (0.59) L3MBTL1KAT6ALARS1F2PRSS1
SCHEMBL3267161 0.79 F2 (0.62) L3MBTL1KAT6ALARS1F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7179579-B2 Radiation-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 2007-02-20 US disclosed