Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 4/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.48 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.48 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408532 | 0.88 | TRPV6 (0.62) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL3639412 | 0.79 | MAPT (0.41) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL29950753 | 0.79 | MAPT (0.41) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL7177934 | 0.72 | TRPV6 (0.52) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL2405808 | 0.71 | TRPV6 (0.72) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL30366540 | 0.71 | HPRT1 (0.46) | ALDH1A1TSHRCXCR5KDM4EMPI | |
| SCHEMBL6562728 | 0.71 | HPRT1 (0.46) | ALDH1A1TSHRCXCR5KDM4EMPI | |
| SCHEMBL2399844 | 0.69 | TRPV6 (0.48) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| Diphenyl Borinic Acid SCHEMBL40601 | 0.68 | TRPV6 (1.00) | TRPV6ORAI1ORAI2ORAI3PCSK9 | |
| SCHEMBL29953524 | 0.67 | MAPT (0.36) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140947-A1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | Basell Polyolefine GmbH (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037476-A1 | METHOD FOR PRODUCING MONO-ORGANOBORANES OR DI-ORGANOBORANES | BASELL POLYOLEFINE GMBH (DE) | 2000-06-29 | — | — | WO | disclosed |