SCHEMBL7782808

SCHEMBL7782808

O=C(c1ccccc1)c1cccc(S(=O)(=O)O)c1O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MAPT P10636 3/20 0.51
ALDH1A1 P00352 3/20 0.51
LMNA P02545 1/20 0.51
AKR1C3 P42330 1/20 0.48
GAA P10253 2/20 0.46
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALOX15 P16050 1/20 0.45
MAPK1 P28482 1/20 0.45
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.42
USP2 O75604 1/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
LIG1 P18858 1/20 0.41
BCL2 P10415 1/20 0.41
MCL1 Q07820 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300439 0.85 AKR1C3 (0.55) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL1161088 0.84 AKR1C3 (0.50) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL28340031 0.84 AKR1C3 (0.53) KMT2AMAPTALDH1A1LMNAAKR1C3
Water SCHEMBL27666388 0.84 AKR1C3 (0.53) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL29496654 0.84 AKR1C3 (0.53) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL30640363 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EALOX15TDP1
SCHEMBL296105 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10KDM4EALOX15TDP1
SCHEMBL2893168 0.81 MAPT (0.53) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL7782795 0.81 AKR1C3 (0.47) KMT2AMAPTALDH1A1LMNAAKR1C3
SCHEMBL7787656 0.81 KMT2A (0.50) KMT2AMAPTALDH1A1LMNAAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181691-A1 HAIR WASHING COMPOSITION 花王株式会社 2023-09-28 WO disclosed
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
EP-0672405-B1 Hair treatment composition KAO CORP (JP) 2001-11-14 EP disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 KMT2A 671/4885MAPT 2404/4885ALDH1A1 494/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 KMT2A 2574/4885MAPT 2556/4885ALDH1A1 6/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 KMT2A 1517/4885MAPT 1450/4885ALDH1A1 201/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 KMT2A 671/4885MAPT 2404/4885ALDH1A1 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.