SCHEMBL2893168

SCHEMBL2893168

Nc1c(C(=O)c2ccccc2)cccc1S(=O)(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
GAA P10253 1/20 0.53
AKR1C3 P42330 1/20 0.47
LMNA P02545 4/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
GLA P06280 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PBRM1 Q86U86 1/20 0.43
MAPK14 Q16539 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
ADORA1 P30542 2/20 0.43
ELANE P08246 1/20 0.43
POLB P06746 1/20 0.42
ABCB11 O95342 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293432 0.88 TTR (0.48) GAAALDH1A1HSD17B10TSHRTTR
SCHEMBL27526847 0.87 MAPT (0.53) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL300439 0.84 AKR1C3 (0.55) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL1161088 0.83 AKR1C3 (0.50) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL8135822 0.83 GAA (0.49) MAPTGAAAKR1C3LMNAKMT2A
Water SCHEMBL27666388 0.82 AKR1C3 (0.53) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL524233 0.82 CASP7 (0.55) MAPTLMNAKMT2AALDH1A1MEN1
SCHEMBL28340031 0.82 AKR1C3 (0.53) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL29496654 0.82 AKR1C3 (0.53) MAPTGAAAKR1C3LMNAKMT2A
SCHEMBL7782808 0.81 KMT2A (0.51) MAPTGAAAKR1C3LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023181691-A1 HAIR WASHING COMPOSITION 花王株式会社 2023-09-28 WO disclosed
US-20220226216-A1 HAIR TREATMENT METHOD KAO CORPORATION (JP) 2022-07-21 US disclosed
EP-3998060-A1 HAIR COSMETIC Kao Corporation (JP) 2022-05-18 EP disclosed
US-11234916-B2 Hair cosmetic KAO CORPORATION (JP) 2022-02-01 US disclosed
EP-3395323-B1 METHOD FOR TREATING HAIR KAO CORP (JP) 2021-09-29 EP disclosed
US-20210069081-A1 HAIR COSMETIC KAO CORPORATION (JP) 2021-03-11 US disclosed
EP-3741352-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 2020-11-25 EP disclosed
US-20190038532-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-02-07 US disclosed
EP-3395323-A1 HAIR TREATMENT METHOD Kao Corporation (JP) 2018-10-31 EP disclosed
US-20100286149-A1 NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS NEUROSEARCH A/S (DK) 2010-11-11 US disclosed
EP-0743847-B1 HAIR COSMETIC COMPOSITION KAO CORP (JP) 2001-05-30 EP disclosed
US-6217855-B1 ELASTICITY KAO CORPORATION (JP) 2001-04-17 US disclosed
EP-0662314-B1 Method of hair treatment KAO CORP (JP) 1999-11-03 EP disclosed
US-5683685-A NAPHTHALENESULFONIC ACID AND/OR BENZOPHENONE SULFONIC ACID WITH ANIONIC AND/OR AMPHOTERIC SURFACTANT WITH OIL KAO CORPORATION (JP) 1997-11-04 US disclosed
EP-0743847-A1 HAIR COSMETIC COMPOSITION Kao Corporation (JP) 1996-11-27 EP disclosed
EP-0529437-B1 Hair treatment composition KAO CORP (JP) 1996-07-17 EP disclosed
EP-0672405-A1 Hair treatment composition KAO CORPORATION (JP) 1995-09-20 EP disclosed
WO-1995020375-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 1995-08-03 WO disclosed
EP-0662314-A1 Method of hair treatment Kao Corporation (JP) 1995-07-12 EP disclosed
EP-0529437-A1 Hair treatment composition Kao Corporation (JP) 1993-03-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210069081-A1 HAIR COSMETIC TYR, CUTA, H1-0 MAPT 2404/4885GAA 1978/4885AKR1C3 2468/4885
US-20220226216-A1 HAIR TREATMENT METHOD POLR1C, ALDH7A1, CA7 MAPT 2556/4885GAA 2027/4885AKR1C3 69/4885
US-20190038532-A1 METHOD FOR TREATING HAIR TYR, POLR1C, CA7 MAPT 1450/4885GAA 2602/4885AKR1C3 239/4885
US-11234916-B2 Hair cosmetic TYR, CUTA, H1-0 MAPT 2404/4885GAA 1978/4885AKR1C3 2468/4885
US-20100286149-A1 NOVEL BENZAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS KCNA2, KCNJ2, KCNB2 MAPT 2500/4885GAA 1524/4885AKR1C3 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.