Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | RHEB | Q15382 | 5/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782884 | 0.93 | MAPT (0.39) | MEN1KMT2ARHEBMAPTHTT | |
| SCHEMBL7778163 | 0.89 | CHEK2 (0.36) | MEN1KMT2ARHEBFAAHKCNH2 | |
| SCHEMBL7783637 | 0.87 | PDE7A (0.47) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL8664038 | 0.83 | KDM4E (0.34) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL8798565 | 0.75 | KDM4E (0.43) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL9015117 | 0.75 | GCGR (0.50) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL29172448 | 0.73 | GCGR (0.38) | MEN1KMT2AMAPTHTTNPSR1 | |
| SCHEMBL3893100 | 0.70 | KDM4E (0.46) | MEN1KMT2AHTTKDM4EHPGD | |
| SCHEMBL8415325 | 0.69 | MAPK14 (0.56) | MEN1KMT2ASMN1; SMN2MAPK14KDM4E | |
| Bromide SCHEMBL29618239 | 0.69 | KDM4E (0.45) | MEN1KMT2AHTTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |