Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894859 | 0.82 | SLC6A3 (0.48) | MAPK14NOTUMNPC1RAB9AALDH1A1 | |
| SCHEMBL15510789 | 0.77 | GPR35 (0.43) | NOTUMALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9015117 | 0.75 | GCGR (0.50) | MAPK14ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8798565 | 0.75 | KDM4E (0.43) | MAPK14NOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL27537767 | 0.74 | BACE1 (0.43) | MAPK14NOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL29172448 | 0.73 | GCGR (0.38) | MAPK14ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2662896 | 0.72 | MAPK14 (1.00) | MAPK14 | |
| SCHEMBL8663128 | 0.71 | KDM4E (0.35) | KDM1AALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL3558851 | 0.70 | FABP4 (0.43) | NOTUMNPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL8664038 | 0.70 | KDM4E (0.34) | MAPK14ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934930-A1 | Process for the preparation of 2-aryl-5-(perfluoroalkyl)pyrrole compounds from N-(perfluoroalkylmethyl)arylimidoyl chloride compounds | American Cyanamid Company (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0816337-A1 | A process for the manufacture of 2 aryl 5 perfluoroalkylpyrrole derivatives and intermediates useful therefor | American Cyanamid Company (US) | 1998-01-07 | — | — | EP | disclosed |