SCHEMBL7784985

SCHEMBL7784985

NCCOB(O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.56
TAAR1 Q96RJ0 1/20 0.45
PNMT P11086 1/20 0.42
TSHR P16473 2/20 0.41
MAPK1 P28482 2/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
TRPM2 O94759 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
IDO1 P14902 2/20 0.41
HTR3E A5X5Y0 1/20 0.41
HTR3B O95264 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23858271 0.81 MGLL (0.59) MGLLTSHRMAPK1MEN1ALDH1A1
SCHEMBL27909142 0.77 MGLL (0.67) MGLLPNMTTSHRMAPK1ALDH1A1
SCHEMBL14703844 0.76 MGLL (0.65) MGLLTSHRMAPK1ALDH1A1TDP1
SCHEMBL27932331 0.76 MGLL (0.65) MGLLPNMTTSHRMAPK1ALDH1A1
SCHEMBL5373777 0.73 TAAR1 (0.45) TAAR1PNMTTSHRMAPK1KDM4E
SCHEMBL4995 0.73 MGLL (1.00) MGLLTSHRMAPK1KDM4EALDH1A1
Trifluoromethylbenzene SCHEMBL10445339 0.72 TRPV6 (0.50) MGLLTSHRMEN1ALDH1A1CYP1A2
SCHEMBL14503485 0.70 KDM4E (0.48) MGLLTAAR1TSHRMAPK1KDM4E
SCHEMBL3524104 0.69 L3MBTL1 (0.59) TAAR1KDM4EALDH1A1ALOX15MAOB
SCHEMBL1668314 0.69 MGLL (0.58) MGLLTSHRMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed