Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785173 | 0.89 | ALDH1A1 (0.45) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7785657 | 0.88 | SMN1; SMN2 (0.37) | KMT2AMAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL7789422 | 0.84 | ABCB1 (0.40) | KMT2AMAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL7785112 | 0.82 | KMT2A (0.44) | KMT2AMAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL27533539 | 0.81 | NPC1 (0.46) | KMT2AMAPTMAPK1ALDH1A1POLB | |
| SCHEMBL27533545 | 0.81 | NPC1 (0.46) | KMT2AMAPTMAPK1ALDH1A1POLB | |
| SCHEMBL7785523 | 0.81 | MAPT (0.40) | KMT2AMAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL7787494 | 0.78 | KMT2A (0.38) | KMT2AMAPTSMN1; SMN2MEN1MAPK1 | |
| SCHEMBL7780324 | 0.76 | CRHBP (0.47) | KMT2AMAPTSMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7804229 | 0.76 | ALDH1A1 (0.42) | KMT2AALDH1A1TDP1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |