Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803588 | 0.88 | TUBB4A (0.42) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL7785272 | 0.76 | KMT2A (0.41) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL7785657 | 0.75 | SMN1; SMN2 (0.37) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL27533545 | 0.74 | NPC1 (0.46) | ALDH1A1RAB9AABCB1KMT2A | |
| SCHEMBL27533539 | 0.74 | NPC1 (0.46) | ALDH1A1RAB9AABCB1KMT2A | |
| SCHEMBL17323188 | 0.74 | TUBB4A (0.46) | ALDH1A1TDP1TUBB4ATUBBTUBA3C | |
| SCHEMBL7804239 | 0.74 | TDP1 (0.51) | ALDH1A1TDP1RAB9AHSPB1PTGS2 | |
| SCHEMBL7804329 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1RAB9AGRM8GRM4 | |
| SCHEMBL7785541 | 0.72 | TTR (0.59) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL8731827 | 0.71 | TPMT (0.43) | TDP1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |