SCHEMBL77854

SCHEMBL77854

CCCC(=O)C(O)C(O)(C(=O)CCC)C(O)C(=O)CCC

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HDAC3 O15379 4/20 0.33
HDAC1 Q13547 4/20 0.33
HDAC2 Q92769 4/20 0.33
HDAC8 Q9BY41 4/20 0.33
FFAR3 O14843 3/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.31
FAAH O00519 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4085632 0.89 CES2 (0.47) CES2CES1FAAH
SCHEMBL4087697 0.89 CES2 (0.47) CES2CES1FAAH
SCHEMBL4080554 0.87 CES2 (0.48) CES2CES1FAAH
SCHEMBL28995646 0.85 FAAH (0.47) CES2CES1FAAH
SCHEMBL2126954 0.85 FAAH (0.47) CES2CES1FAAH
SCHEMBL9754746 0.82 FAAH (0.48) CES2CES1FAAH
SCHEMBL25299017 0.80 FAAH (0.50) CES2CES1FAAH
SCHEMBL2733841 0.80 FAAH (0.50) CES2CES1FAAH
SCHEMBL17540757 0.80 FAAH (0.50) CES2CES1FAAH
SCHEMBL2827903 0.80 FAAH (0.50) CES2CES1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11413350-B2 Long-acting polymeric delivery systems HERON THERAPEUTICS, INC. (US) 2022-08-16 US disclosed
EP-3936115-A1 LONG-ACTING POLYMERIC DELIVERY SYSTEMS Heron Therapeutics, Inc. (US) 2022-01-12 EP disclosed
EP-2831253-B1 ENZYMES USEFUL FOR PERACID PRODUCTION DUPONT US HOLDING LLC (US) 2021-11-24 EP disclosed
EP-2831250-B1 ENZYMES USEFUL FOR PERACID PRODUCTION DUPONT US HOLDING LLC (US) 2021-11-24 EP disclosed
EP-2831226-B1 ENZYMES USEFUL FOR PERACID PRODUCTION DUPONT US HOLDING LLC (US) 2021-11-24 EP disclosed
EP-2831251-B1 ENZYMES USEFUL FOR PERACID PRODUCTION DUPONT US HOLDING LLC (US) 2021-11-24 EP disclosed
EP-2831252-B1 ENZYMES USEFUL FOR PERACID PRODUCTION DUPONT US HOLDING LLC (US) 2021-11-24 EP disclosed
US-11083730-B2 Long-acting polymeric delivery systems HERON THERAPEUTICS, INC. (US) 2021-08-10 US disclosed
US-11083797-B2 Long-acting polymeric delivery systems HERON THERAPEUTICS, INC. (US) 2021-08-10 US disclosed
US-20210220474-A1 LONG-ACTING POLYMERIC DELIVERY SYSTEMS HERON THERAPEUTICS, INC. 2021-07-22 US disclosed
US-20080176783-A1 Production of Peracids Using An Enzyme Having Perhydrolysis Activity DUPONT US HOLDING, LLC 2008-07-24 US disclosed
US-20070184999-A1 Enzymatic production of peracids using lactobacilli having perhydrolysis activity E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-09 US disclosed
US-20070082832-A1 Enzymatic production of peracids from carboxylic acid ester substrates using non-heme haloperoxidases E. I. DU PONT DE NEMOURS AND COMPANY 2007-04-12 US disclosed
EP-0740697-B1 ENZYMES FOR RECREATIONAL WATER BUCKMAN LABOR INC (US) 2003-04-23 EP disclosed
EP-1224870-A1 Use of tributyrin in animal feed and corresponding feed additive Xeris (FR) 2002-07-24 EP disclosed
EP-0740697-A1 ENZYMES FOR RECREATIONAL WATER BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1996-11-06 EP disclosed
US-5507952-A REDUCING AMOUNT OF ACYLGLYCEROL ESTERS IN WATER BY TREATING WITH MIXTURE OF LIPASE ENZYME, NONIONIC EMULSIFYING AGENT, WATER SOLUBLE UNSATURATED ORGANIC ACID PRESERVATIVE, POLYOL STABILIZER BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1996-04-16 US disclosed
US-5474701-A Reducing the amount of glycerol esters with a composition comprising a lipase enzyme, a nonionic emulsifier, a preservative and stabilizer BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-12-12 US disclosed
WO-1995020033-A1 ENZYMES FOR RECREATIONAL WATER BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) 1995-07-27 WO disclosed
WO-1991007168-A1 RIBOFLAVIN AS A TANNING ENHANCER SCHERING-PLOUGH HEALTHCARE PRODUCTS, INC. (US) 1991-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11413350-B2 Long-acting polymeric delivery systems ALOX15, TNNC1, ALOX5 CES2 307/4885CES1 620/4885HDAC3 2369/4885
US-11083797-B2 Long-acting polymeric delivery systems ALOX15, TNNC1, ALOX5 CES2 307/4885CES1 620/4885HDAC3 2369/4885
US-20210220474-A1 LONG-ACTING POLYMERIC DELIVERY SYSTEMS ALOX15, TNNC1, ALOX5 CES2 307/4885CES1 620/4885HDAC3 2369/4885
US-11083730-B2 Long-acting polymeric delivery systems ALOX15, TNNC1, ALOX5 CES2 307/4885CES1 620/4885HDAC3 2369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.