Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785223 | 1.00 | ADRB2 (0.36) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7785653 | 0.92 | SLC6A2 (0.36) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7787615 | 0.91 | MAPKAPK2 (0.33) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL7780536 | 0.89 | IDO1 (0.39) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL7780766 | 0.89 | IDO1 (0.39) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL7789259 | 0.89 | ADRB2 (0.35) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7785573 | 0.89 | ADRB2 (0.35) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7785286 | 0.88 | LMNA (0.35) | SLC6A2SLC6A4CYP3A4CYP2D6SLC6A3 | |
| SCHEMBL7785101 | 0.87 | ADRB2 (0.36) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7785260 | 0.87 | SLC6A9 (0.36) | ADRB2AKT1SLC6A2SLC6A4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |