Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785662 | 0.93 | MAPT (0.48) | LMNAMAPTMEN1CYP3A4CYP2C9 | |
| SCHEMBL7194908 | 0.90 | ITGB3 (0.51) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7790080 | 0.90 | MEN1 (0.52) | MAPTMEN1KMT2ASMN1; SMN2ITGB3 | |
| SCHEMBL7786246 | 0.88 | ITGB3 (0.46) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7788754 | 0.87 | ITGB3 (0.51) | MAPTMEN1KMT2AF2ITGB3 | |
| SCHEMBL7789975 | 0.87 | ITGB3 (0.46) | LMNAMAPTMEN1CYP3A4CYP2C9 | |
| SCHEMBL7786217 | 0.86 | KMT2A (0.46) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7781212 | 0.85 | ITGB3 (0.48) | MAPTMEN1CYP2C9CYP2C19KMT2A | |
| SCHEMBL7790184 | 0.85 | MEN1 (0.48) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7790169 | 0.85 | ITGB3 (0.49) | LMNAMAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |