Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786246 | 0.91 | ITGB3 (0.46) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL7194908 | 0.89 | ITGB3 (0.51) | KMT2AMEN1ITGB3ITGA2BLMNA | |
| SCHEMBL7788754 | 0.88 | ITGB3 (0.51) | KMT2AMEN1ITGB3ITGA2BPKM | |
| SCHEMBL7790184 | 0.88 | MEN1 (0.48) | KMT2AMEN1ITGB3ITGA2BLMNA | |
| SCHEMBL7789975 | 0.88 | ITGB3 (0.46) | KMT2AMEN1ITGB3ITGA2BLMNA | |
| SCHEMBL7781212 | 0.88 | ITGB3 (0.48) | KMT2AMEN1ITGB3ITGA2BMAPT | |
| SCHEMBL7790080 | 0.87 | MEN1 (0.52) | KMT2AMEN1ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7781187 | 0.86 | GAA (0.47) | KMT2AMEN1ITGB3ITGA2BLMNA | |
| SCHEMBL7785662 | 0.86 | MAPT (0.48) | KMT2AMEN1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL7785609 | 0.86 | LMNA (0.45) | KMT2AMEN1ALDH1A1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |