Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785221 | 0.93 | ALDH1A1 (0.64) | ALDH1A1GAALMNACYP3A4MAPT | |
| SCHEMBL7780334 | 0.84 | ALDH1A1 (0.70) | ALDH1A1GAALMNACYP3A4MAPT | |
| SCHEMBL7789426 | 0.83 | ALDH1A1 (0.74) | ALDH1A1GAALMNACYP3A4MAPT | |
| SCHEMBL7780585 | 0.80 | KMT2A (0.54) | ALDH1A1GAALMNACYP3A4MAPT | |
| SCHEMBL12350147 | 0.79 | MEN1 (0.54) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL27540196 | 0.77 | ACP3 (0.50) | ALDH1A1GAALMNAMAPTNPC1 | |
| SCHEMBL7785642 | 0.77 | ACP3 (0.50) | ALDH1A1GAALMNAMAPTNPC1 | |
| SCHEMBL10155639 | 0.76 | MAPT (0.47) | ALDH1A1GAALMNAMAPTNPC1 | |
| SCHEMBL7787446 | 0.76 | MAPT (0.52) | ALDH1A1LMNAMAPTNPC1RAB9A | |
| SCHEMBL7787584 | 0.76 | MEN1 (0.49) | ALDH1A1GAALMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |