Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26287035 | 0.94 | TLR8 (0.40) | TLR8ICMTCNR2CTSSCTSK | |
| SCHEMBL6715464 | 0.93 | TLR8 (0.42) | TLR8ICMTCTSSCTSKSPHK2 | |
| SCHEMBL1130701 | 0.90 | TLR8 (0.37) | TLR8ICMTCNR2CTSSCTSK | |
| Tetramethylammonium Ion SCHEMBL1130664 | 0.89 | TLR8 (0.40) | TLR8ICMTCTSSCTSKSPHK2 | |
| Tetramethylammonium Ion SCHEMBL29470085 | 0.89 | TLR8 (0.40) | TLR8ICMTCTSSCTSKSPHK2 | |
| SCHEMBL1130405 | 0.88 | TLR8 (0.37) | TLR8ICMTCNR2CTSSCTSK | |
| Tetrabuthylammonium SCHEMBL1130718 | 0.86 | TLR8 (0.39) | TLR8ICMTCTSSCTSKSPHK2 | |
| SCHEMBL26287046 | 0.85 | NFE2L2 (0.40) | TLR8ICMTCTSSCTSKSPHK2 | |
| SCHEMBL1130778 | 0.85 | DNM1 (0.41) | TLR8HDAC3HDAC1HDAC2SIGMAR1 | |
| SCHEMBL29440637 | 0.82 | DNM1 (0.39) | TLR8SIGMAR1TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880075-B1 | Radiation sensitive resin composition | JSR CORP (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-5958648-A | Radiation sensitive resin composition | JSR CORPORATION (JP) | 1999-09-28 | — | — | US | disclosed |
| EP-0880075-A1 | Radiation sensitive resin composition | JSR Corporation (JP) | 1998-11-25 | — | — | EP | disclosed |