SCHEMBL6715464

SCHEMBL6715464

CCCCCC[B-](c1cccc(C(F)(F)F)c1)(c1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 1/20 0.42
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
ICMT O60725 1/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
TRPV1 Q8NER1 1/20 0.38
SPHK2 Q9NRA0 1/20 0.38
SPHK1 Q9NYA1 1/20 0.38
HTR2A P28223 2/20 0.37
HTR2B P41595 2/20 0.37
HTR2C P28335 1/20 0.37
EPHX1 P07099 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
SLC6A4 P31645 2/20 0.37
LMNA P02545 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26287035 0.96 TLR8 (0.40) TLR8HDAC3HDAC1HDAC2ICMT
Tetramethylammonium Ion SCHEMBL1130664 0.96 TLR8 (0.40) TLR8HDAC3HDAC1HDAC2ICMT
Biphenyl SCHEMBL7785983 0.93 TLR8 (0.41) TLR8HDAC3HDAC1HDAC2ICMT
Tetrabuthylammonium SCHEMBL1130718 0.93 TLR8 (0.39) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL26287046 0.92 NFE2L2 (0.40) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL1130701 0.91 TLR8 (0.37) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL1130405 0.89 TLR8 (0.37) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL26287052 0.87 GABRA2 (0.37) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL1130810 0.86 TLR8 (0.35) TLR8HDAC3HDAC1HDAC2ICMT
SCHEMBL1130778 0.86 DNM1 (0.41) TLR8HDAC3HDAC1HDAC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10001703-B2 Photopolymer formulation for production of holographic media comprising borates with low TG COVESTRO DEUTSCHLAND AG (DE) 2018-06-19 US disclosed
US-10001703-B2 Photopolymer formulation for production of holographic media comprising borates with low TG COVESTRO DEUTSCHLAND AG (DE) 2018-06-19 US disclosed
EP-3058423-B1 PHOTOPOLYMER FORMULATION FOR PRODUCING HOLOGRAPHIC MEDIA WITH LOW TG BORATES COVESTRO DEUTSCHLAND AG (DE) 2018-04-18 EP disclosed
EP-1413924-A1 COMPOSITION HAVING PERMITIVITY BEING RADIATION-SENSITIVELY CHANGEABLE AND METHOD FOR FORMING PERMITIVITY PATTERN JSR Corporation (JP) 2004-04-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10001703-B2 Photopolymer formulation for production of holographic media comprising borates with low TG PTGIS, TST, MACF1 TLR8 4730/4885HDAC3 3514/4885HDAC1 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.