Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5051543 | 1.00 | CYP2D6 (0.50) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL7784261 | 0.84 | ADRA2A (0.62) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL5055098 | 0.84 | ADRA2A (0.62) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL5051458 | 0.83 | ADRA2A (0.71) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL7786327 | 0.83 | ADRA2A (0.71) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9868612 | 0.83 | MEN1 (0.63) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9869689 | 0.82 | MEN1 (0.71) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL9945918 | 0.79 | L3MBTL1 (0.46) | ADRA1AMEN1KMT2AMAPK1KDM4E | |
| SCHEMBL5050115 | 0.78 | ALDH1A1 (0.48) | CYP2D6ADRA2AADRA1AMEN1KMT2A | |
| SCHEMBL7779145 | 0.78 | ALDH1A1 (0.48) | CYP2D6ADRA2AADRA1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |